Which hormone decreases the production of follicle-stimulating hormone (FSH) as its levels rise in the blood?

Estrogen plays a crucial role in the regulation of the reproductive hormones in the body, particularly in relation to follicle-stimulating hormone (FSH). As the levels of estrogen rise in the bloodstream, particularly during the follicular phase of the menstrual cycle, it feeds back to the anterior pituitary gland to inhibit the release of FSH. By doing this, estrogen helps to regulate the growth and maturation of ovarian follicles, ensuring that only a limited number develop and preventing excessive follicle stimulation.

This feedback mechanism is an essential part of the hormonal balance necessary for reproductive health and helps to maintain the proper function of the menstrual cycle. The role of estrogen in decreasing FSH is part of a complex spiral of hormonal interactions, ultimately contributing to ovulation and the overall reproductive process.